Increased Thyroid-Hormone Requirements Consistent With Type 3 Deiodinase Induction Related to Ibrutinib in a Thyroidectomized Woman

Increased Thyroid-Hormone Requirements Consistent With Type 3 Deiodinase Induction Related to Ibrutinib in a Thyroidectomized Woman

Objective: Tyrosine-kinase inhibitors (TKIs) are chemotherapeutic agents associated with increased thyroid-hormone requirements and altered deiodinase activity. We present the first case to link these findings to the TKI ibrutinib. Methods: Serial thyroid-stimulating hormone (TSH), free-thyroxine (F...

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Bibliographic Details
Main Authors: Alon Yehuda Mazori, MD, Maria Skamagas, MD
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:AACE Clinical Case Reports
Subjects:
tyrosine kinase inhibitors
thyroid hormones
deiodinase
hypothyroidism
side effects
cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2376060520310269

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http://www.sciencedirect.com/science/article/pii/S2376060520310269

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