Elucidating the expression and function of Numbl during cell adhesion-mediated drug resistance (CAM-DR) in multiple myeloma (MM)

Abstract Background Cell adhesion-mediated drug resistance (CAM-DR) is a major clinical problem that prevents successful treatment of multiple myeloma (MM). In particular, the expression levels of integrin β1 and its sub-cellular distribution (internalization and trafficking) are strongly associated...

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Bibliographic Details
Main Authors: Yuejiao Huang, Xianting Huang, Chun Cheng, Xiaohong Xu, Hong Liu, Xiaojing Yang, Li Yao, Zongmei Ding, Jie Tang, Song He, Yuchan Wang
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Cancer
Subjects:
MM
Online Access:https://doi.org/10.1186/s12885-019-6446-y