Disturbed Blood Flow Acutely Increases Endothelial Microparticles and Decreases Flow Mediated Dilation in Patients With Heart Failure With Reduced Ejection Fraction

Disturbed Blood Flow Acutely Increases Endothelial Microparticles and Decreases Flow Mediated Dilation in Patients With Heart Failure With Reduced Ejection Fraction

IntroductionDisturbed blood flow, characterized by high retrograde and oscillatory shear rate (SR), is associated with a proatherogenic phenotype. The impact of disturbed blood flow in patients with heart failure with reduced ejection fraction (HFrEF) remains unknown. We tested the hypothesis that a...

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Bibliographic Details
Main Authors: Thiago O. C. Silva, Allan R. K. Sales, Gustavo S. M. Araujo, Guilherme W. P. Fonseca, Pedro G. S. Braga, Diego Faria, Helena N. M. Rocha, Natalia G. Rocha, Marta F. Lima, Charles Mady, Carlos E. Negrão, Maria Janieire N. N. Alves
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Physiology
Subjects:
disturbed blood flow
endothelial microparticles
endothelial function
heart failure
vascular
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.629674/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.629674/full

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