A slow axon antidromic blockade hypothesis for tremor reduction via deep brain stimulation.

Parkinsonian and essential tremor can often be effectively treated by deep brain stimulation. We propose a novel explanation for the mechanism by which this technique ameliorates tremor: a reduction of the delay in the relevant motor control loops via preferential antidromic blockade of slow axons....

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Bibliographic Details
Main Authors: Míriam R García, Barak A Pearlmutter, Peter E Wellstead, Richard H Middleton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24066049/?tool=EBI