Salvianolic Acid B Protects Against Fatty Acid-Induced Renal Tubular Injury via Inhibition of Endoplasmic Reticulum Stress

Salvianolic Acid B Protects Against Fatty Acid-Induced Renal Tubular Injury via Inhibition of Endoplasmic Reticulum Stress

Background/Aims: Obesity-related kidney disease is associated with elevated levels of saturated free fatty acids (SFA). SFA lipotoxicity in tubular cells contributes to significant cellular apoptosis and injury. Salvianolic acid B (SalB) is the most abundant bioactive molecule from Radix Salviae Mil...

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Bibliographic Details
Main Authors: Xiaoyi Mai, Xin Yin, Peipei Chen, Minzhou Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pharmacology
Subjects:
salvianolic acid B
renal tubular injury
saturated fatty acid
apoptosis
ER stress
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.574229/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.574229/full

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