In vitro thermodynamic dissection of human copper transfer from chaperone to target protein.

Transient protein-protein and protein-ligand interactions are fundamental components of biological activity. To understand biological activity, not only the structures of the involved proteins are important but also the energetics of the individual steps of a reaction. Here we use in vitro biophysic...

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Bibliographic Details
Main Authors: Moritz S Niemiec, Christoph F Weise, Pernilla Wittung-Stafshede
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3344837?pdf=render