Quantitative Modeling of Protein Synthesis Using Ribosome Profiling Data

Quantitative prediction on protein synthesis requires accurate translation initiation and codon translation rates. Ribosome profiling data, which provide steady-state distribution of relative ribosome occupancies along a transcript, can be used to extract these rate parameters. Various methods have...

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Bibliographic Details
Main Authors: Vandana Yadav, Inayat Ullah Irshad, Hemant Kumar, Ajeet K. Sharma
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.688700/full