Long-Term Memory Engram Cells Are Established by c-Fos/CREB Transcriptional Cycling

Summary: Training-dependent increases in c-fos have been used to identify engram cells encoding long-term memories (LTMs). However, the interaction between transcription factors required for LTM, including CREB and c-Fos, and activating kinases such as phosphorylated ERK (pERK) in the establishment...

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Bibliographic Details
Main Authors: Tomoyuki Miyashita, Emi Kikuchi, Junjiro Horiuchi, Minoru Saitoe
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718317686