Increased immune complexes of hypocretin autoantibodies in narcolepsy.

BACKGROUND: Hypocretin peptides participate in the regulation of sleep-wake cycle while deficiency in hypocretin signaling and loss of hypocretin neurons are causative for narcolepsy-cataplexy. However, the mechanism responsible for alteration of the hypocretin system in narcolepsy-cataplexy and its...

Full description

Bibliographic Details
Main Authors: Aude Deloumeau, Sophie Bayard, Quentin Coquerel, Pierre Déchelotte, Christine Bole-Feysot, Bertrand Carlander, Valérie Cochen De Cock, Sergueï O Fetissov, Yves Dauvilliers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2954157?pdf=render