Imidazolines as Non-Classical Bioisosteres of N-Acyl homoserine lactones and Quorum Sensing Inhibitors

Imidazolines as Non-Classical Bioisosteres of N-Acyl homoserine lactones and Quorum Sensing Inhibitors

A series of selected 2-substituted imidazolines were synthesized in moderate to excellent yields by a modification of protocols reported in the literature. They were evaluated as potential non-classical bioisosteres of AHL with the aim of counteracting bacterial pathogenicity. Imidazolines 18a, 18e...

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Bibliographic Details
Main Authors: Mabel Montenegro-Sustaita, Everardo Curiel-Quesada, Héctor Salgado-Zamora, Alicia Reyes-Arellano, Alejandro Bucio-Cano
Format: Article
Language:English
Published: MDPI AG 2012-01-01
Series:International Journal of Molecular Sciences
Subjects:
imidazoline synthesis
quorum sensing
Chromobacterium violaceum
AHL bioisosteres
Online Access:http://www.mdpi.com/1422-0067/13/2/1284/

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http://www.mdpi.com/1422-0067/13/2/1284/

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