Unmasking the Role of Uptake Transporters for Digoxin Uptake Across the Barriers of the Central Nervous System in Rat

Unmasking the Role of Uptake Transporters for Digoxin Uptake Across the Barriers of the Central Nervous System in Rat

The role of uptake transporter (organic anion–transporting polypeptide [Oatp]) in the disposition of a P-glycoprotein (P-gp) substrate (digoxin) at the barriers of central nervous system, namely, the blood-brain barrier (BBB), blood-spinal cord barrier (BSCB), and brain-cerebrospinal fluid barrier (...

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Bibliographic Details
Main Authors: Kunal S Taskar, T Thanga Mariappan, Vishwanath Kurawattimath, Shashyendra Singh Gautam, TV Radhakrishna Mullapudi, Srikanth K Sridhar, Raja Reddy Kallem, Punit Marathe, Sandhya Mandlekar
Format: Article
Language:English
Published: SAGE Publishing 2017-03-01
Series:Journal of Central Nervous System Disease
Online Access:https://doi.org/10.1177/1179573517693596

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https://doi.org/10.1177/1179573517693596

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