Quantification of mitochondrial DNA copy number in suspected cancer patients by a well optimized ddPCR method
Changes in mitochondrial DNA (mtDNA) content is a useful clinical biomarker for various diseases, however results are controversial as several analytical factors can affect measurement of mtDNA. MtDNA is often quantified by taking ratio between a target mitochondrial gene and a reference nuclear gen...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-09-01
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| Series: | Biomolecular Detection and Quantification |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221475351730205X |