Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations

Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations

Abstract Background Invasive cribriform and intraductal carcinoma (CR/IDC) is associated with adverse outcome of prostate cancer patients. The aim of this study was to determine the molecular aberrations associated with CR/IDC in primary prostate cancer, focusing on genomic instability and somatic c...

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Bibliographic Details
Main Authors: René Böttcher, Charlotte F. Kweldam, Julie Livingstone, Emilie Lalonde, Takafumi N. Yamaguchi, Vincent Huang, Fouad Yousif, Michael Fraser, Robert G. Bristow, Theodorus van der Kwast, Paul C. Boutros, Guido Jenster, Geert J. L. H. van Leenders
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Cancer
Subjects:
Cribriform
Intraductal carcinoma
Prostate cancer
Copy number alteration
Aggressive disease
Genomic instability
Online Access:http://link.springer.com/article/10.1186/s12885-017-3976-z

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http://link.springer.com/article/10.1186/s12885-017-3976-z

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