Active transcription and Orc1 drive chromatin association of the AAA+ ATPase Pch2 during meiotic G2/prophase.

Pch2 is an AAA+ protein that controls DNA break formation, recombination and checkpoint signaling during meiotic G2/prophase. Chromosomal association of Pch2 is linked to these processes, and several factors influence the association of Pch2 to euchromatin and the specialized chromatin of the riboso...

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Bibliographic Details
Main Authors: Richard Cardoso da Silva, María Ascensión Villar-Fernández, Gerben Vader
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008905