Regulation of protein synthesis in lymphoblasts from vanishing white matter patients

Regulation of protein synthesis in lymphoblasts from vanishing white matter patients

Leukoencephalopathy with vanishing white matter (VWM) is an inherited childhood white matter disorder, caused by mutations in the genes encoding eukaryotic initiation factor 2B (eIF2B). The present study showed that, while the eIF2B activity was reduced in VWM lymphoblasts, the expression levels of...

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Bibliographic Details
Main Authors: Barbara van Kollenburg, Adri A.M. Thomas, Gerre Vermeulen, Gesina A.M. Bertrand, Carola G.M. van Berkel, Jan C. Pronk, Christopher G. Proud, Marjo S. van der Knaap, Gert C. Scheper
Format: Article
Language:English
Published: Elsevier 2006-03-01
Series:Neurobiology of Disease
Subjects:
Translation
White matter
eIF2B
Heat shock
Leukoencephalopathy
Childhood
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105002378

Internet

http://www.sciencedirect.com/science/article/pii/S0969996105002378

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