Hand Osteoarthritis: investigating Pain Effects of estrogen-containing therapy (HOPE-e): a protocol for a feasibility randomised placebo-controlled trial

Hand Osteoarthritis: investigating Pain Effects of estrogen-containing therapy (HOPE-e): a protocol for a feasibility randomised placebo-controlled trial

Abstract Background Hand osteoarthritis (OA) is a common condition, causing pain, stiffness and reduced quality of life. Incidence is higher amongst women, particularly around the age of the menopause. Whilst the relationship between sex hormones and OA has been studied in vitro, in epidemiological...

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Bibliographic Details
Main Authors: Ioana R. Marian, Megan Goff, Jennifer A. E. Williams, Malvika Gulati, Mae Chester-Jones, Anne Francis, Marion Watson, Tonia L. Vincent, Sue Woollacott, Charles Mackworth-Young, Victoria Glover, Dominic Furniss, Matthew Gardiner, Sarah E. Lamb, Katy Vincent, Vicki S. Barber, Joanna Black, Susan J. Dutton, Fiona E. Watt
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Pilot and Feasibility Studies
Subjects:
Hand osteoarthritis
Estrogen
Hormone replacement therapy
Clinical trial
Feasibility
Online Access:https://doi.org/10.1186/s40814-021-00869-1

Internet

https://doi.org/10.1186/s40814-021-00869-1

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