A Toolbox for Predicting G-Quadruplex Formation and Stability

G-quadruplexes are four stranded nucleic acid structures formed around a core of guanines, arranged in squares with mutual hydrogen bonding. Many of these structures are highly thermally stable, especially in the presence of monovalent cations, such as those found under physiological conditions. Und...

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Bibliographic Details
Main Authors: Han Min Wong, Oliver Stegle, Simon Rodgers, Julian Leon Huppert
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.4061/2010/564946