Clozapine Worsens Glucose Intolerance, Nonalcoholic Fatty Liver Disease, Kidney Damage, and Retinal Injury and Increases Renal Reactive Oxygen Species Production and Chromium Loss in Obese Mice

Clozapine Worsens Glucose Intolerance, Nonalcoholic Fatty Liver Disease, Kidney Damage, and Retinal Injury and Increases Renal Reactive Oxygen Species Production and Chromium Loss in Obese Mice

Clozapine is widely employed in the treatment of schizophrenia. Compared with that of atypical first-generation antipsychotics, atypical second-generation antipsychotics such as clozapine have less severe side effects and may positively affect obesity and blood glucose level. However, no systematic...

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Bibliographic Details
Main Authors: Geng-Ruei Chang, Hsien-Yueh Liu, Wei-Cheng Yang, Chao-Min Wang, Ching-Fen Wu, Jen-Wei Lin, Wei-Li Lin, Yu-Chen Wang, Tzu-Chun Lin, Huei-Jyuan Liao, Po-Hsun Hou, Chee-Hong Chan, Chuen-Fu Lin
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
chromium
clozapine
fatty liver disease
glucose intolerance
obesity
renal damage
Online Access:https://www.mdpi.com/1422-0067/22/13/6680

Internet

https://www.mdpi.com/1422-0067/22/13/6680

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