Growth Hormone Mediates Its Protective Effect in Hepatic Apoptosis through Hnf6.

Growth hormone (GH) not only supports hepatic metabolism but also protects against hepatocyte cell death. Hnf6 (or Oc1) belonging to the Onecut family of hepatocyte transcription factors known to regulate differentiated hepatic function, is a GH-responsive gene. We evaluate if GH mediates Hnf6 activ...

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Bibliographic Details
Main Authors: Kewei Wang, Minhua Wang, Maureen Gannon, AiXuan Holterman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5147851?pdf=render