Characterization of ectonucleotidases in human medulloblastoma cell lines: ecto-5'NT/CD73 in metastasis as potential prognostic factor.

Medulloblastoma (MB) is the most common malignant brain tumor in children and occurs mainly in the cerebellum. Important intracellular signaling molecules, such those present in the Sonic Hedgehog and Wnt pathways, are involved in its development and can also be employed to determine tumor grade and...

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Main Authors: Angélica Regina Cappellari, Liliana Rockenbach, Fabrícia Dietrich, Vanessa Clarimundo, Talita Glaser, Elizandra Braganhol, Ana Lúcia Abujamra, Rafael Roesler, Henning Ulrich, Ana Maria Oliveira Battastini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23094051/?tool=EBI