High-glucose diets induce mitochondrial dysfunction in Caenorhabditis elegans.

Glucose is an important nutrient that dictates the development, fertility and lifespan of all organisms. In humans, a deficit in its homeostatic control might lead to hyperglucemia and the development of obesity and type 2 diabetes, which show a decreased ability to respond to and metabolize glucose...

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Main Authors: Jonathan Alcántar-Fernández, Angélica González-Maciel, Rafael Reynoso-Robles, Martha Elva Pérez Andrade, Alain de J Hernández-Vázquez, Antonio Velázquez-Arellano, Juan Miranda-Ríos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0226652