Genetic polymorphisms of organic cation transporters 1 (OCT1) and responses to metformin therapy in individuals with type 2 diabetes mellitus: a systematic review protocol

Genetic polymorphisms of organic cation transporters 1 (OCT1) and responses to metformin therapy in individuals with type 2 diabetes mellitus: a systematic review protocol

Abstract Background Metformin is one of the most commonly used drugs for type 2 diabetes mellitus (T2DM). Despite its efficacy and safety, metformin is frequently associated with highly variable glycemic responses, which is hypothesized to be the result of genetic variations in its transport by orga...

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Bibliographic Details
Main Authors: Edith Pascale Mofo Mato, Magellan Guewo-Fokeng, M. Faadiel Essop, Peter Mark Oroma Owira
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Systematic Reviews
Subjects:
Genetic polymorphisms
Glycemic response
Metformin
OCT1
Type 2 diabetes mellitus
Online Access:http://link.springer.com/article/10.1186/s13643-018-0773-y

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http://link.springer.com/article/10.1186/s13643-018-0773-y

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