Effect of female genital schistosomiasis and anti-schistosomal treatment on monocytes, CD4+ T-cells and CCR5 expression in the female genital tract.

BACKGROUND: Schistosoma haematobium is a waterborne parasite that may cause female genital schistosomiasis (FGS), characterized by genital mucosal lesions. There is clinical and epidemiological evidence for a relationship between FGS and HIV. We investigated the impact of FGS on HIV target cell dens...

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Bibliographic Details
Main Authors: Elisabeth Kleppa, Veron Ramsuran, Siphosenkosi Zulu, Gunn Hege Karlsen, Alfred Bere, Jo-Ann S Passmore, Patricia Ndhlovu, Kristine Lillebø, Sigve D Holmen, Mathias Onsrud, Svein Gunnar Gundersen, Myra Taylor, Eyrun F Kjetland, Thumbi Ndung'u
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4045760?pdf=render