Mouse TRIP13/PCH2 is required for recombination and normal higher-order chromosome structure during meiosis.
Accurate chromosome segregation during meiosis requires that homologous chromosomes pair and become physically connected so that they can orient properly on the meiosis I spindle. These connections are formed by homologous recombination closely integrated with the development of meiosis-specific, hi...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-08-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2920839?pdf=render |