Role of glioblastoma stem cells in cancer therapeutic resistance: a perspective on antineoplastic agents from natural sources and chemical derivatives

Role of glioblastoma stem cells in cancer therapeutic resistance: a perspective on antineoplastic agents from natural sources and chemical derivatives

Abstract Glioblastoma (GBM) is the highest-grade form of glioma, as well as one of the most aggressive types of cancer, exhibiting rapid cellular growth and highly invasive behavior. Despite significant advances in diagnosis and therapy in recent decades, the outcomes for high-grade gliomas (WHO gra...

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Bibliographic Details
Main Authors: Ana Laura V. Alves, Izabela N. F. Gomes, Adriana C. Carloni, Marcela N. Rosa, Luciane S. da Silva, Adriane F. Evangelista, Rui Manuel Reis, Viviane Aline O. Silva
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Stem Cell Research & Therapy
Subjects:
Chemoradioresistance
Clinical trials
Glial stem cell
Initiating cells
Therapeutic strategies
Natural products
Online Access:https://doi.org/10.1186/s13287-021-02231-x

Internet

https://doi.org/10.1186/s13287-021-02231-x

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