Direct Comparison of Radiolabeled Probes FMAU, FHBG, and FHPG as PET Imaging Agents for HSV1-tk Expression in a Human Breast Cancer Model

2′-Deoxy-2′-fluoro-5-methyl-1-β- d -arabinofuranosyluracil (FMAU), 9-(4-fluoro-3-hydroxy-methyl-butyl)guanine (FHBG) and 9-[(3-fluoro-1-hydroxy-2-propoxy)methyl]-guanine (FHPG) have been evaluated in a human breast cancer model as potential radiotracers for PET imaging of HSV1-tk gene expression. In...

Full description

Bibliographic Details
Main Authors: Mian M. Alauddin, Atranik Shahinian, Erlinda M. Gordon, Peter S. Conti
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2004-04-01
Series:Molecular Imaging
Online Access:https://doi.org/10.1162/15353500200403160