ZnT8-Specific CD4+ T cells display distinct cytokine expression profiles between type 1 diabetes patients and healthy adults.

ZnT8-Specific CD4+ T cells display distinct cytokine expression profiles between type 1 diabetes patients and healthy adults.

Determination of antigen-specific T cell repertoires in human blood has been a challenge. Here, we show a novel integrated approach that permits determination of multiple parameters of antigen-specific T cell repertoires. The approach consists of two assays: the Direct assay and the Cytokine-driven...

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Bibliographic Details
Main Authors: Daisuke Chujo, Emile Foucat, Thien-Son Nguyen, Damien Chaussabel, Jacques Banchereau, Hideki Ueno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3563599?pdf=render

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http://europepmc.org/articles/PMC3563599?pdf=render

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