MGMT Leu84Phe polymorphism contributes to cancer susceptibility: evidence from 44 case-control studies.

BACKGROUND: O(6)-methylguanine-DNA methyltransferase is one of the few proteins to directly remove alkylating agents in the human DNA direct reversal repair pathway. A large number of case-control studies have been conducted to explore the association between MGMT Leu84Phe polymorphism and cancer ri...

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Bibliographic Details
Main Authors: Jun Liu, Renxia Zhang, Fei Chen, Cuicui Yu, Yan Sun, Chuanliang Jia, Lijing Zhang, Taufiq Salahuddin, Xiaodong Li, Juntian Lang, Xicheng Song
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3784571?pdf=render