Imbalance of heterologous protein folding and disulfide bond formation rates yields runaway oxidative stress
<p>Abstract</p> <p>Background</p> <p>The protein secretory pathway must process a wide assortment of native proteins for eukaryotic cells to function. As well, recombinant protein secretion is used extensively to produce many biologics and industrial enzymes. Therefore,...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-03-01
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| Series: | BMC Biology |
| Subjects: | |
| Online Access: | http://www.biomedcentral.com/1741-7007/10/16 |