Function and Dysfunction of Complement Factor H During Formation of Lipid-Rich Deposits

Complement-mediated inflammation or dysregulation in lipid metabolism are associated with the pathogenesis of several diseases. These include age-related macular degeneration (AMD), C3 glomerulonephritis (C3GN), dense deposit disease (DDD), atherosclerosis, and Alzheimer’s disease (AD). In all these...

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Bibliographic Details
Main Authors: Seppo Meri, Karita Haapasalo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
HDL
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.611830/full