Redox state and mitochondrial respiratory chain function in skeletal muscle of LGMD2A patients.

Redox state and mitochondrial respiratory chain function in skeletal muscle of LGMD2A patients.

Calpain-3 deficiency causes oxidative and nitrosative stress-induced damage in skeletal muscle of LGMD2A patients, but mitochondrial respiratory chain function and anti-oxidant levels have not been systematically assessed in this clinical population previously.We identified 14 patients with phenotyp...

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Bibliographic Details
Main Authors: Mats I Nilsson, Lauren G Macneil, Yu Kitaoka, Fatimah Alqarni, Rahul Suri, Mahmood Akhtar, Maria E Haikalis, Pavneet Dhaliwal, Munim Saeed, Mark A Tarnopolsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4117472?pdf=render

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http://europepmc.org/articles/PMC4117472?pdf=render

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