Rab6a/a' are important Golgi regulators of pro-inflammatory TNF secretion in macrophages.

Rab6a/a' are important Golgi regulators of pro-inflammatory TNF secretion in macrophages.

Lipopolysaccharide (LPS)-activated macrophages secrete pro-inflammatory cytokines, including tumor necrosis factor (TNF) to elicit innate immune responses. Secretion of these cytokines is also a major contributing factor in chronic inflammatory disease. In previous studies we have begun to elucidate...

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Bibliographic Details
Main Authors: Massimo Micaroni, Amanda C Stanley, Tatiana Khromykh, Juliana Venturato, Colin X F Wong, Jet P Lim, Brad J Marsh, Brian Storrie, Paul A Gleeson, Jennifer L Stow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3578815?pdf=render

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http://europepmc.org/articles/PMC3578815?pdf=render

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