Chronic obstructive pulmonary disease candidate gene prioritization based on metabolic networks and functional information.

Chronic obstructive pulmonary disease (COPD) is a multi-factor disease, in which metabolic disturbances played important roles. In this paper, functional information was integrated into a COPD-related metabolic network to assess similarity between genes. Then a gene prioritization method was applied...

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Bibliographic Details
Main Authors: Xinyan Wang, Wan Li, Yihua Zhang, Yuyan Feng, Xilei Zhao, Yuehan He, Jun Zhang, Lina Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5584748?pdf=render