Upregulation of MIF as a defense mechanism and a biomarker of Alzheimer’s disease

Abstract Background Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine. Chronic inflammation induced by amyloid β proteins (Aβ) is one prominent neuropathological feature in Alzheimer’s disease (AD) brain. Methods Elisa, Western blot, and immunohistochemical staining analysi...

Full description

Bibliographic Details
Main Authors: Si Zhang, Jiehao Zhao, Yuhu Zhang, Yun Zhang, Fang Cai, Lijuan Wang, Weihong Song
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Alzheimer’s Research & Therapy
Subjects:
MIF
Online Access:http://link.springer.com/article/10.1186/s13195-019-0508-x