Increases in Endogenous or Exogenous Progestins Promote Virus-Target Cell Interactions within the Non-human Primate Female Reproductive Tract.

Currently, there are mounting data suggesting that HIV-1 acquisition in women can be affected by the use of certain hormonal contraceptives. However, in non-human primate models, endogenous or exogenous progestin-dominant states are shown to increase acquisition. To gain mechanistic insights into th...

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Bibliographic Details
Main Authors: Ann M Carias, Shannon A Allen, Angela J Fought, Katarina Kotnik Halavaty, Meegan R Anderson, Maria L Jimenez, Michael D McRaven, Casey J Gioia, Tara R Henning, Ellen N Kersh, James M Smith, Lara E Pereira, Katherine Butler, S Janet M McNicholl, R Michael Hendry, Patrick F Kiser, Ronald S Veazey, Thomas J Hope
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5033389?pdf=render