Cytokine-defined B cell responses as Therapeutic Targets in Multiple Sclerosis

Cytokine-defined B cell responses as Therapeutic Targets in Multiple Sclerosis

Important antibody-independent pathogenic roles of B cells are emerging in autoimmune diseases including multiple sclerosis (MS). The contrasting results of different treatments targeting B cells in patients (in spite of predictions of therapeutic benefits from animal models) call for a better under...

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Bibliographic Details
Main Authors: Rui eLi, Ayman eRezk, Luke eHealy, Gillian eMuirhead, Alexandre ePrat, Jennifer L Gommerman, Amit eBar-Or
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Immunology
Subjects:
B-Lymphocytes
Multiple Sclerosis
Immune Modulation
B-cell depletion
Cytokine-defined responses
B cell modulation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00626/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00626/full

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