Extracellular vesicle integrins act as a nexus for platelet adhesion in cerebral microvessels

Abstract Circulating extracellular vesicles (EVs) regulate signaling pathways via receptor-ligand interactions and content delivery, after attachment or internalization by endothelial cells. However, they originate from diverse cell populations and are heterogeneous in composition. To determine the...

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Bibliographic Details
Main Authors: Zsolt Bagi, Yvonne Couch, Zuzana Broskova, Francisco Perez-Balderas, Tianrong Yeo, Simon Davis, Roman Fischer, Nicola R. Sibson, Benjamin G. Davis, Daniel C. Anthony
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-52127-3