Synergistic Effect of Baicalin and Adriamycin in Resistant HL-60/ADM Leukaemia Cells

Synergistic Effect of Baicalin and Adriamycin in Resistant HL-60/ADM Leukaemia Cells

Background/Aims: The present study was designed to investigate the expression of multidrug resistance (MDR)-related genes, verify the synergistic effects of baicalin and Adriamycin (ADM) and investigate the related mechanisms in ADM-resistant leukaemic HL-60/ADM cells. Methods: We used a HL-60/ADM c...

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Bibliographic Details
Main Authors: Jing Zheng, Tetsuya Asakawa, Yingyu Chen, Zhihong Zheng, Buyuan Chen, Minhui Lin, Tingbo Liu, Jianda Hu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Baicalin
Adriamycin
Leukaemic HL-60/ADM cells
Multidrug resistance
PI3K/Akt signalling pathway
Online Access:http://www.karger.com/Article/FullText/480420

Internet

http://www.karger.com/Article/FullText/480420

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