Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy

Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy

Recent studies have proposed that intracellular water is different from bulk water at the molecular level. Here the authors introduce a Raman microscopy-based method to image the distribution of water states in living cells, and report intracellular water heterogeneity between nucleus and cytoplasm....

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Main Authors: Lixue Shi, Fanghao Hu, Wei Min
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12708-2
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spelling doaj-80cf5a5763e74dca843764790eb9fa802021-05-11T12:15:26ZengNature Publishing GroupNature Communications2041-17232019-10-011011810.1038/s41467-019-12708-2Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopyLixue Shi0Fanghao Hu1Wei Min2Department of Chemistry, Columbia UniversityDepartment of Chemistry, Columbia UniversityDepartment of Chemistry, Columbia UniversityRecent studies have proposed that intracellular water is different from bulk water at the molecular level. Here the authors introduce a Raman microscopy-based method to image the distribution of water states in living cells, and report intracellular water heterogeneity between nucleus and cytoplasm.https://doi.org/10.1038/s41467-019-12708-2
collection DOAJ
language English
format Article
sources DOAJ
author Lixue Shi
Fanghao Hu
Wei Min
spellingShingle Lixue Shi
Fanghao Hu
Wei Min
Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy
Nature Communications
author_facet Lixue Shi
Fanghao Hu
Wei Min
author_sort Lixue Shi
title Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy
title_short Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy
title_full Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy
title_fullStr Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy
title_full_unstemmed Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy
title_sort optical mapping of biological water in single live cells by stimulated raman excited fluorescence microscopy
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2019-10-01
description Recent studies have proposed that intracellular water is different from bulk water at the molecular level. Here the authors introduce a Raman microscopy-based method to image the distribution of water states in living cells, and report intracellular water heterogeneity between nucleus and cytoplasm.
url https://doi.org/10.1038/s41467-019-12708-2
work_keys_str_mv AT lixueshi opticalmappingofbiologicalwaterinsinglelivecellsbystimulatedramanexcitedfluorescencemicroscopy
AT fanghaohu opticalmappingofbiologicalwaterinsinglelivecellsbystimulatedramanexcitedfluorescencemicroscopy
AT weimin opticalmappingofbiologicalwaterinsinglelivecellsbystimulatedramanexcitedfluorescencemicroscopy
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