Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy

Recent studies have proposed that intracellular water is different from bulk water at the molecular level. Here the authors introduce a Raman microscopy-based method to image the distribution of water states in living cells, and report intracellular water heterogeneity between nucleus and cytoplasm....

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Bibliographic Details
Main Authors: Lixue Shi, Fanghao Hu, Wei Min
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12708-2