Claudin-2 Expression Levels in Ulcerative Colitis: Development and Validation of an In-Situ Hybridisation Assay for Therapeutic Studies.

Claudin-2 Expression Levels in Ulcerative Colitis: Development and Validation of an In-Situ Hybridisation Assay for Therapeutic Studies.

Ulcerative colitis is a chronic inflammatory disease affecting the colon and is characterized by epithelial damage and barrier dysfunction. Upregulation of the tight junction protein claudin-2 by cytokines is hypothesized to contribute to the dysregulation of the epithelial barrier. New therapeutic...

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Bibliographic Details
Main Authors: Kevin Randall, Neil Henderson, Jaimini Reens, Sonia Eckersley, Ann-Christin Nyström, Marie C South, Clare A Balendran, Gerhard Böttcher, Glen Hughes, Sally A Price
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5012586?pdf=render

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http://europepmc.org/articles/PMC5012586?pdf=render

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