The Causal Role of Mitochondrial Dynamics in Regulating Innate Immunity in Diabetes

The Causal Role of Mitochondrial Dynamics in Regulating Innate Immunity in Diabetes

Background: Plenty of evidence suggested that chronic low-grade inflammation triggered by innate immunity activation contributes to the pathogenesis of type 2 diabetes (T2D). Using the trans-mitochondrial cybrid cell model, we have demonstrated that mitochondria independently take part in the pathol...

Full description

Bibliographic Details
Main Authors: Yen-Hsiang Chang, Hung-Yu Lin, Feng-Chih Shen, Yu-Jih Su, Jiin-Haur Chuang, Tsu-Kung Lin, Chia-Wei Liou, Ching-Yi Lin, Shao-Wen Weng, Pei-Wen Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Endocrinology
Subjects:
mitochondrial dynamics
innate immunity
type 2 diabetes
nutrient excess
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00445/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2020.00445/full

Similar Items