Targeted nanodiamonds for identification of subcellular protein assemblies in mammalian cells.

Transmission electron microscopy (TEM) can be used to successfully determine the structures of proteins. However, such studies are typically done ex situ after extraction of the protein from the cellular environment. Here we describe an application for nanodiamonds as targeted intensity contrast lab...

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Bibliographic Details
Main Authors: Michael P Lake, Louis-S Bouchard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5479563?pdf=render