Low number of KIR ligands in lymphoma patients favors a good rituximab-dependent NK cell response

Low number of KIR ligands in lymphoma patients favors a good rituximab-dependent NK cell response

The antibody-dependent cellular cytotoxicity (ADCC) effector function of natural killer (NK) cells is one of the known mechanisms of action for rituximab-based anti-cancer immunotherapy. Inhibition of the ADCC function of NK cells through interactions between inhibitory killer cell immunoglobulin-li...

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Bibliographic Details
Main Authors: Dhon Roméo Makanga, Maxime Jullien, Gaëlle David, Nolwenn Legrand, Catherine Willem, Léa Dubreuil, Alexandre Walencik, Cyrille Touzeau, Thomas Gastinne, Benoit Tessoulin, Steven Le Gouill, Béatrice Mahé, Katia Gagne, Patrice Chevallier, Béatrice Clemenceau, Christelle Retière
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
kir
hla
adcc
rituximab
nk cells
cd16
non hodgkin lymphoma
Online Access:http://dx.doi.org/10.1080/2162402X.2021.1936392

Internet

http://dx.doi.org/10.1080/2162402X.2021.1936392

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