Evaluation of a Microhaplotype-Based Noninvasive Prenatal Test in Twin Gestations: Determination of Paternity, Zygosity, and Fetal Fraction

Evaluation of a Microhaplotype-Based Noninvasive Prenatal Test in Twin Gestations: Determination of Paternity, Zygosity, and Fetal Fraction

As a novel type of genetic marker, the microhaplotype has shown promising potential in forensic research. In the present study, we analyzed maternal plasma cell-free DNA (cfDNA) samples from twin pregnancies to validate microhaplotype-based noninvasive prenatal testing (NIPT) for paternity, zygosity...

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Bibliographic Details
Main Authors: Zhaochen Bai, Hu Zhao, Shaobin Lin, Linhuan Huang, Zhiming He, Huan Wang, Xueling Ou
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Genes
Subjects:
microhaplotype
non-invasive prenatal testing
twins
paternity
zygosity
fetal fraction
Online Access:https://www.mdpi.com/2073-4425/12/1/26

Internet

https://www.mdpi.com/2073-4425/12/1/26

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