Inhibition of LINE-1 Retrotransposition by Capsaicin

Inhibition of LINE-1 Retrotransposition by Capsaicin

Long interspersed nuclear element 1 (LINE-1 or L1) is a non-long terminal repeat (LTR) retrotransposon that constitutes approximately 17% of the human genome. Since approximately 100 copies are still competent for retrotransposition to other genomic loci, dysregulated retrotransposition of L1 is con...

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Bibliographic Details
Main Authors: Yuki Nishikawa, Ryota Nakayama, Shunsuke Obika, Eriko Ohsaki, Keiji Ueda, Tomoyuki Honda
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
anti-cancer
capsaicin
inhibitor
LINE-1
L1
phytochemicals
retrotransposition
reverse transcriptase
Online Access:http://www.mdpi.com/1422-0067/19/10/3243

Internet

http://www.mdpi.com/1422-0067/19/10/3243

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