Regulation of Calcium Channel α1A Subunit Splice Variant mRNAs in Kainate-Induced Temporal Lobe Epilepsy

P/Q-type voltage-gated Ca2+ channels (VGCC) regulate neurotransmitter release in the hippocampus and molecular alterations of their α1A pore-forming subunits are involved in various animal and human CNS diseases. We evaluated, using RT-PCR and in situ hybridization, the spatio-temporal activation of...

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Bibliographic Details
Main Authors: S Vigues, M Gastaldi, C Chabret, A Massacrier, P Cau, J Valmier
Format: Article
Language:English
Published: Elsevier 1999-08-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996199902486