Advanced Research on Dopamine Signaling to Develop Drugs for the Treatment of Mental Disorders: Ser311Cys Polymorphisms of the Dopamine D2–Receptor Gene and Schizophrenia
Schizophrenia is a debilitating and complex mental disorder with a prevalence of approximately 1% worldwide. The etiology remains unclear, despite massive research efforts. Hyperactive dopaminergic signal transduction in the central nervous system is suggested to be involved in the pathophysiology o...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2010-01-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319308734 |