Functional Validation of a New Alginate-based Hydrogel Scaffold Combined with Mesenchymal Stem Cells in a Rat Hard Palate Cleft Model

Background:. One of the major difficulties in cleft palate repair is the requirement for several surgical procedures and autologous bone grafting to form a bony bridge across the cleft defect. Engineered tissue, composed of a biomaterial scaffold and multipotent stem cells, may be a useful alternati...

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Main Authors: Marie Naudot, PhD, Julien Davrou, MD, Az-Eddine Djebara, MD, Anaïs Barre, MS, Nolwenn Lavagen, MD, Sandrine Lardière, PhD, Soufiane Zakaria Azdad, MD, Luciane Zabijak, BS, Stéphane Lack, PhD, Bernard Devauchelle, MD, Jean-Pierre Marolleau, MD, Sophie Le Ricousse, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2020-04-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002743