Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery

<p>Abstract</p> <p>Background</p> <p>Treatment of cells with the anti-cancer drug 5-fluorouracil (5-FU) causes DNA damage, which in turn affects cell proliferation and survival. Two stable wild-type <it>TP53 </it>5-FU-resistant cell lines, ContinB and Contin...

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Bibliographic Details
Main Authors: Kravik Katherine L, Svendsrud Debbie H, De Angelis Paula M, Stokke Trond
Format: Article
Language:English
Published: BMC 2006-05-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/5/1/20